Knowledge of eukaryotic life cycles and associated genome dynamics stems largely from research on animals, plants, and a small number of “model” (i.e., easily cultivable) lineages. This skewed sampling results in an underappreciation of the variability among the many microeukaryotic lineages, which represent the bulk of eukaryotic biodiversity. The range of complex nuclear transformations that exists within lineages of microbial eukaryotes challenges the textbook understanding of genome and nuclear cycles. Here, we look in‐depth at Foraminifera, an ancient (∼600 million‐year‐old) lineage (...) widely studied as proxies in paleoceanography and environmental biomonitoring. We demonstrate that Foraminifera challenge the “rules” of life cycles developed largely from studies of plants and animals. To this end, we synthesize data on foraminiferal life cycles, focusing on extensive endoreplication within individuals (i.e., single cells), the unusual nuclear process calledZerfall, and the separation of germline and somatic function into distinct nuclei (i.e., heterokaryosis). These processes highlight complexities within lineages and expand our understanding of the dynamics of eukaryotic genomes. (shrink)

This paper proposes a methodological synthesis in order to study multimodal media discourse and argumentation in the context of the so-called ‘refugee crisis’ in Greece. It follows the framework of Multimodal Critical Discourse Analysis, integrating this with argumentation studies, with a particular emphasis on the analysis of inference. Our data come from the Greek newspapers Kathimerini and Ta Nea. We contend that the proposed methodological synergy enables scrutiny of (a) racist conceptualizations cultivated by the representation of migrants and refugees in (...) headlines and photographs in newspaper articles along with (b) the argumentative potential that is implicitly sustained in these multimodal representations. (shrink)

Online controlled experiments, also known as A/B tests, have become ubiquitous. While many practical challenges in running experiments at scale have been thoroughly discussed, the ethical dimension of A/B testing has been neglected. This article fills this gap in the literature by introducing a new, soft ethics and governance framework that explicitly recognizes how the rise of an experimentation culture in industry settings brings not only unprecedented opportunities to businesses but also significant responsibilities. More precisely, the article (a) introduces a (...) set of principles to encourage ethical and responsible experimentation to protect users, customers, and society; (b) argues that ensuring compliance with the proposed principles is a complex challenge unlikely to be addressed by resorting to a one-solution response; (c) discusses the relevance and effectiveness of several mechanisms and policies in educating, governing, and incentivizing companies conducting online controlled experiments; and (d) offers a list of prompting questions specifically designed to help and empower practitioners by stimulating specific ethical deliberations and facilitating coordination among different groups of stakeholders. (shrink)

A number of virtue epistemologists endorse the following thesis: Knowledge is true belief resulting from intellectual virtue, where Ss true belief results from intellectual virtue just in case S believes the truth because S is intellectually virtuous. This thesis commits one to a sort of contextualism about knowledge attributions. This is because, in general, sentences of the form X occurred because Y occurred require a contextualist treatment. This sort of contextualism is contrasted with more familiar versions. It is argued that (...) the position: (a) yields a better solution to the lottery problem, and (b) may be grounded in a more general theory of virtue and credit. (shrink)

The purpose of this volume is to provide a relatively complete guide to the current state of epistemology. To this end, each essay addresses some important issue in the theory of knowledge. Each provides some historical background or other contextual information so as to orient the reader to the problem at hand and to its current state of development. After this, each author provides an extended defense of his or her own position on the relevant topic. In this way the (...) essays go well beyond simple introductions. They are attempts to (a) locate the current state of an important question in epistemology, and (b) move discussion forward from that point. (shrink)

On Death, by the Epicurean philosopher Philodemus of Gadara, is among the most significant philosophical treatments of the theme surviving from the Greco-Roman world. The author was an influential figure in first-century B.C.E. Roman society, associated with poets such as Virgil and politicians such as the father-in-law of Julius Caesar. The surviving copies of his treatises were carbonized following the eruption of Vesuvius in 79 C.E. This edition contains the Greek text, newly reconstituted with the help of the infrared (...) imaging technology that has revolutionized the study of Philodemus’s works in the twenty-first century, and completely translated into English for the first time. An extensive introduction provides background on Philodemus and his writings, accompanying notes enrich the text, and forty-four pages of photographs illustrate the papyrus manuscript from which the translation is drawn. (shrink)

One’s first reaction on seeing this book might be to wonder why it is labelled "Aristotle" at all. The de Mundo has long been regarded as spurious, the work of a later Peripatetic, or even of the vaguely Stoicizing eclecticism which was already, in the later Hellenistic period, beginning to see Aristotle and Plato as the proponents of the same philosophy. There has, however, been no general agreement about where precisely in that framework it should be placed, and Reale, who (...) has recently tried, not without success, to rehabilitate Melissus as a serious thinker, now tries to rehabilitate the de Mundo as a genuine work of Aristotle: he thinks the lack of agreement among the critics is itself an argument in its favor. Restoring the original attribution seems to be the main purpose of what is in fact the first full scale edition with commentary of the de Mundo. It contains a text, largely that established by Lorimer, with translation en face, a long introduction, copious notes and a full word index; the text and translation occupy less than a fifth of the whole. As far as a non-Italian can judge the translation is accurate—and free of effusive expansion. The notes are a real mine of information. So it should be said at the start that whether or not one accepts Reale’s thesis about genuineness does not affect the value of the edition as such. The question of authenticity is discussed with great thoroughness in the introduction, with considerable backing, some of it perhaps inevitably repetitious, in the form of detailed discussion in the notes. At the start Reale lists the charges levelled against the work at various times. These are that in general it contains non-Aristotelian elements, that the style is completely different from Aristotle’s, as is the method, being one of assertion rather than demonstration. Further, much of the material in the scientific section is post-Aristotelian, and the "Orphic hymn" of chapter 7 shows Stoic influence. Reale argues that the first three charges will stick only if the basis of discussion is the Aristotle of the treatises and claims that the objectionable material in the de Mundo can be paralleled from the exoteric works. Thus all the pre-Jaeger discussion is misconceived. (shrink)

In the history of philosophical thought, few themes loom as large as skepticism. Skepticism has been the most visible and important part of debates about knowledge. Skepticism at its most basic questions our cognitive achievements, challenges our ability to obtain reliable knowledge; casting doubt on our attempts to seek and understand the truth about everything from ethics, to other minds, religious belief, and even the underlying structure of matter and reality. Since Descartes, the defense of knowledge against skepticism has been (...) one of the primary tasks not just of epistemology but philosophy itself. The Oxford Handbook of Skepticism features twenty-six newly commissioned chapters by top figures in the field. Part One contains articles explaining important kinds of skeptical reasoning. Part Two focuses on responses to skeptical arguments. Part Three concentrates on important contemporary issues revolving around skepticism. As the first volume of its kind, the articles make significant contributions to the debate on skepticism. (shrink)

Part One reviews some recent history of epistemology, focusing on ways in which the intellectual virtues have been invoked to solve specific epistemological problems. This part gives a sense of the contemporary landscape that has emerged and clarifies some of the disagreements among those who invoke the virtues in epistemology. Part Two explores some problems about knowledge in greater detail, and defends a externalist approach in virtue epistemology.

O presente trabalho tem por objetivo debater a ideia de que o enunciado pode vir a ser uma provável categoria de análise, na tentativa de pensar o(s) discurso(s), do mesmo modo que sua geração, na moldura teórica proposta por Michel Foucault (1926-1984). O filósofo francês desenvolveu o enunciado como uma categoria de análise, em obras como As Palavras e As Coisas (1966) e a A Arqueologia do Saber (1969), em um enquadramento capaz de permitir uma determinada autonomia à formulação de (...) um conceito. Desta forma, o enunciado, na tentativa de engendrar essa mesma autonomia a uma teoria a ser erigida, permitiria a gravitação desta nos referidos discursos produzidos pelo indivíduo. O enunciado, foucaultianamente, não se refere em stricto sensu a um arcabouço gramatical, ou estritamente linguístico, mas permite a confluência na formação de noções teóricas, ou mesmo na moldura do(s) discurso(s), possibilitando a consonância de ideias que fundamentam os discursos vigentes nas ciências humanas e que delineiam o status quo. Sendo a proposição de enunciado em Foucault uma categoria não necessariamente científica, isto é, sem a envergadura de uma composição de verdade, assim como de um “dizer verdadeiro”. O enunciado, na proposta do autor, contrapõe-se ao discurso que versa sobre a nomenclatura da verdade e os mecanismos que instituem a constante produção desta e que outorgam as concepções epistemológicas (que constituem as epistemologias vigorantes) nos espaços: social, político, histórico e também cultural. (shrink)

In Ancient Science and Dreams, M. Andrew Holowchak analyzes the ancient notion of science of dreams throughout Greco-Roman antiquity, from the Classical Greece in the fifth century B.C. to the Roman Republic in the fourth century A.D. Holowchak investigates psycho-physiological accounts, interpretation of prophetic dreams, and the use of dreams in secular and non-secular medicine.

This article reviews some recent history of epistemology, focusing on ways in which the intellectual virtues have been invoked to solve specific epistemological problems. It gives a sense of the contemporary landscape that has emerged, and clarifies some of the disagreements among those who invoke the virtues in epistemology. Furthermore, it explores some epistemological problems in greater detail. It also defends a particular approach in virtue epistemology by displaying its power in addressing these problems. It pursues the idea that a (...) minimalist, reliabilist notion of the intellectual virtues is useful for constructing an account of knowledge. It sets out to support this on the ground that this approach to intellectual virtue can adequately address three major problems in the theory of knowledge: Humean skepticism, the Gettier problem, and the problem of showing that knowledge is more valuable than mere true belief. (shrink)

There are various forms of teleological thinking central to debates in the early modern and modern periods, debates in which David Hume (1711–1776) is a key figure. In the first section, we shall introduce three levels at which teleological considerations have been incorporated into philosophical accounts of man and nature, and sketch Hume’s criticisms of these approaches. In the second section, we turn to Hume’s non-teleological ‘science of man’. In the third section, we show how Hume has an account of (...) human flourishing that is not dependent on teleology. In the fourth section, we shall speculate as to the relation between Hume’s account of human nature and contemporary evolutionary accounts of morality and reasoning. (shrink)

In his examination of the concepts of evil and impermanence, entitled “Evil and the Problem of Impermanence in Medieval Japanese Philosophy”, Yujin Nagasawa addresses four responses to the problem of impermanence, arguing that the only satisfactory response to the problem leads to an implication about supernaturalism. As Nagasawa puts it, “the problem of impermanence can be construed as a partial argument for supernaturalism and against naturalism”. In response to Nagasawa, I will take up the challenge of naturalism by trying to (...) deconstruct the arguments against indifferentism in order to reformulate and thus strengthen Nagasawa’s response to the problem of impermanence. I will then turn to the radicalization of this thesis by drawing out implications through a comparison with Dōgen’s thought. (shrink)

In his article ‘God and Probability’, 1 Hugh Mellor introduced the notion of the ‘bridge-hand fallacy’, allegedly committed by those who think they can appeal to probabilities in arguments for design. I should like to give this notion another airing, partly because of its recent criticism in two interesting books - R. G. Swinburne' The Existence of God and D. J. Bartholomew's God of Chance - and partly because it seems worth asking how it fares in relation to the most (...) recent examples of design argument, namely those which appeal to the so-called ‘anthropic principle’ in cosmology. (shrink)